Gangrene is a complication of necrosis Necrosis is the premature death of cells and living tissue. Necrosis is caused by external factors, such as infection, toxins or trauma. This is in contrast to apoptosis, which is a naturally occurring cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental, and can be fatal (i.e., cell The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. Some organisms, such as most bacteria, are unicellular . Other organisms, such as humans, are multicellular. (Humans have an estimated 100 trillion death) characterized by the decay of body tissues Tissue is a cellular organizational level intermediate between cells and a complete organism. Hence, a tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function. Organs are then formed by the functional grouping together of multiple tissues, which become black (and/or green) and malodorous. It is caused by infection An infection is the detrimental colonization of a host organism by a foreign species. In an infection, the infecting organism seeks to utilize the host's resources to multiply, usually at the expense of the host. The infecting organism, or pathogen, interferes with the normal functioning of the host and can lead to chronic wounds, gangrene, loss or ischemia In medicine, ischemia is a restriction in blood supply, generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue. It may also be spelled ischaemia or ischæmia. It also means local anemia in a given part of a body sometimes resulting from vasoconstriction, thrombosis or embolism, such as by the bacteria Clostridium perfringens Clostridium perfringens is a Gram-positive, rod-shaped, anaerobic, spore-forming bacterium of the genus Clostridium. C. perfringens is ubiquitous in nature and can be found as a normal component of decaying vegetation, marine sediment, the intestinal tract of humans and other vertebrates, insects, and soil[1] or by thrombosis Thrombosis is the formation of a blood clot (thrombus) inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel is injured, the body uses platelets and fibrin to form a blood clot, because the first step in repairing it (hemostasis) is to prevent loss of blood. If that mechanism causes too much (blocked blood vessel The blood vessels are the part of the circulatory system that transport blood throughout the body. There are three major types of blood vessels: the arteries, which carry the blood away from the heart, the capillaries, which enable the actual exchange of water and chemicals between the blood and the tissues; and the veins, which carry blood from). It is usually the result of critically insufficient blood Blood is a specialized bodily fluid that delivers necessary substances to the body's cells – such as nutrients and oxygen – and transports waste products away from those same cells supply (e.g., peripheral vascular disease Peripheral vascular disease , also known as peripheral artery disease (PAD) or peripheral artery occlusive disease (PAOD), includes all diseases caused by the obstruction of large arteries in the arms and legs. PVD can result from atherosclerosis, inflammatory processes leading to stenosis, an embolism, or thrombus formation. It causes either) and is often associated with diabetes Diabetes mellitus —often simply referred to as diabetes—is a condition in which a person has a high blood sugar (glucose) level as a result of the body either not producing enough insulin, or because body cells do not properly respond to the insulin that is produced. Insulin is a hormone produced in the pancreas which enables body cells to and long-term smoking. This condition is most common in the lower extremities. The best treatment for gangrene is revascularization Revascularization is "a surgical procedure for the provision of a new, additional, or augmented blood supply to a body part or organ." The term derives from the prefix re-, in this case meaning "restoration" and vasculature, which refers to the circulatory structures of an organ.[citation needed] (i.e., restoration of blood flow) of the affected organ, which can reverse some of the effects of necrosis and allow healing. Other treatments include debridement Debridement is the medical removal of a patient's dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. Removal may be surgical, mechanical, chemical, autolytic , and by maggot therapy, where certain species of live maggots selectively eat only necrotic tissue and surgical amputation Amputation is the removal of a body extremity by trauma or surgery. As a surgical measure, it is used to control pain or a disease process in the affected limb, such as malignancy or gangrene. In some cases, it is carried out on individuals as a preventative surgery for such problems. A special case is the congenital amputation, a congenital. The method of treatment is generally determined depending on location of affected tissue and extent of tissue loss. Gangrene may appear as one effect of foot binding Foot binding was a custom practised on young girls and women for approximately one thousand years in China, beginning in the 10th century and ending in the early 20th century.
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hu, 26 Nov 2009 09:38:59 GM
In an art history course, I remember learning of an artist that died of . gangrene. alone on an island. Now I can't remember the artist and its driving me crazy! Can anyone help? Paul Gauguin died in Tahiti of syphillis close but no ...

