An adverse drug reaction (abbreviated ADR) is an expression that describes harm associated with the use of given medications at a normal dose. The meaning of this expression differs from the meaning of "side effect", as this last expression might also imply that the effects can be beneficial. The study of ADRs is the concern of the field known as pharmacovigilance.

Classification

ADRs may be classified by e.g. cause and severity.

Cause

  • Type A: Augmented pharmacologic effects - dose dependent and predictable
a.Intolerance
b.side effects
  • Type B: Bizarre effects (or idiosyncratic) - dose independent and unpredictable
  • Type C: Chronic effects
  • Type D: Delayed effects
  • Type E: End-of-treatment effects
  • Type F: Failure of therapy

Types A and B were proposed in the 1970s, and the other types were proposed subsequently when the first two proved insufficient to classify ADRs.

From Wikipedia under the GNU Free Documentation License
Fri Sep 3 02:40:57 2010

Has anyone's child has any adverse reactions to the drug Singulair?
Q. Just curious about people's experiences with this drug My son has had some adverse reactions to this drug and wanted to know others' experiences with it.
Asked by kappgal - Mon May 18 20:41:42 2009 - - 1 Answers - 0 Comments

A. I took it for several years and had no problems but I did hear on tv awhile back that children were having a lot of reactions to Singulair.
Answered by Judie(((ST JUDE KIDS))) - Mon May 18 22:08:18 2009

i've had a liver transplant,any adverse reaction to the drugs or swelling in the legs that wont go away?
Q. I had a liver transplant in november 2006,I would like to hear from fellow transplant patients,or medicaly qualified persons on how to cope with the after effects of the operation and is lack of albumin the cause of swelling in my ankles,and taking tacrolemus and azathioprine causing loss of memory and the pain in my body and joints.please reply in plain english not medical gobuldygook .I am looking for long term corespodance.a problem shared is a problem halved. mike
Asked by Tango - Sun Jun 3 01:00:19 2007 - - 6 Answers - 0 Comments

A. here you can find some useful information about how to cope with effects after operation .. .
Answered by Rainierbay S - Mon Jun 4 09:44:19 2007

Can I contest the Tier of a Tier 3 Drug?
Q. I have a medication that is tier 3 with my insurance. I pay $50 a month. There so called cheaper alternative, which is tier 1 generic, makes me vomit. Can I get my insurance company to charge me for only a tier 2 drug on the basis that I have an acute adverse reaction to the cheaper alternative?
Asked by Jens - Sun Mar 8 13:47:47 2009 - - 2 Answers - 0 Comments

From Yahoo Answer Search: "Adverse drug reaction"
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Jury aims to prevent suicides - Toronto Sun
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FDA to Weigh In on Obesity Drug - PharmExec.com
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Reporting forms for adverse drug reactions are located on each nursing unit or can be obtained from clinical pharmacists or by calling ext 8238

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Figure 1 Time to First Occurrence of Primary Endpoint Figure 2 Beneficial Effect of Perindopril Treatment on Primary Endpoint in Predefined Subgroups

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