An adverse drug reaction (abbreviated ADR) is an expression that describes harm associated with the use of given medications at a normal dose. The meaning of this expression differs from the meaning of "side effect", as this last expression might also imply that the effects can be beneficial. The study of ADRs is the concern of the field known as pharmacovigilance.

Classification

ADRs may be classified by e.g. cause and severity.

Cause

  • Type A: Augmented pharmacologic effects - dose dependent and predictable
a. intolerance
b.side effects
  • Type B: Bizarre effects (or idiosyncratic) - dose independent and unpredictable
  • Type C: Chronic effects
  • Type D: Delayed effects
  • Type E: End-of-treatment effects
  • Type F: Failure of therapy

Types A and B were proposed in the 1970s, and the other types were proposed subsequently when the first two proved insufficient to classify ADRs.

From Wikipedia under the GNU Free Documentation License
Sun Jan 31 11:49:52 2010

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Doctors are only human they do NOT have all potential drug interactions memorized After asking your doctor about possible adverse drug reactions for a

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be noted that non steroidal anti inflammatory agents NSAIDs including the COX 2 inhibitors were identified 21 times cephalosporins 20 times penicillins 17 times and opioids 17 times The Important Role of Health Care Professionals Clinical trials effectively assess efficacy and risk benefit ratios but they are generally not large enough to provide all the information

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From Google Blog Search: "Adverse drug reaction"
Fri Feb 5 11:15:42 2010

Drug reactions bulletin bids adieu praising current system - Pharmacy News
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Drug reactions bulletin bids adieu praising current system

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The Australian Adverse Drug Reactions Bulletin has backed the country's spontaneous drug reporting system as "one of the best in the world" in its last ever ...
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From Google News Search: "Adverse drug reaction"
Wed Dec 16 04:51:44 2009

define a severe adverse drug reaction?
Q. define a severe adverse drug reaction?
Asked by rose r - Tue Dec 19 19:32:37 2006 - - 9 Answers - 0 Comments

A. Well, could be hives or anaphylactic (airway swells shut, could die if not promptly treated with adrenaline). Other complications but not true "reactions" would be intestinal bleeding, or respiratory depression. It basically means your body just can't tolerate that drug for one reason or another.
Answered by limeyfan - Tue Dec 19 19:38:45 2006

what is the signs of an adverse reaction to an over the counter drug (naproxen)?
Q. I started feeling like I couldn't think straight, loopy, nauseated,light headedness,dizzy,shakey from inside out,numbness in my extremeties,trouble breathing, just plain strange for several hours and still not feeling well. can anyone help?
Asked by Lisa B - Mon May 18 20:58:54 2009 - - 1 Answers - 0 Comments
can a person have an adverse reaction or even overdose if they take 2mg of xanax if they are non tolerant?
Q. when i say "non tolerant" i mean they have no prior use to benzos. lets say they take a 2mg dose of xanax (which is the highest prescribed dose). will anything bad happen to this person? and no i dont use drugs. but i know alot of people who do and xanax seems to be a popular one. which i dont know why cause it just makes you sleepy.
Asked by opio-coca - Thu Jan 24 19:17:28 2008 - - 1 Answers - 0 Comments

A. Absolutely. People react very differently to the same dosage of drug. I see this all the time in the OR, when we give a "little something" to help relax the patient while the monitors are being put on... sometimes the patient has almost no effect, and other times, they're barely arouseable - from the same small dose. Although older and smaller people TEND to react more to medications, that is not always the case. Sometimes, big strapping young men are profoundly affected. People who use drugs are taking a risk.
Answered by Pangolin - Thu Jan 24 19:31:27 2008

From Yahoo Answer Search: "Adverse drug reaction"
Sun Dec 27 15:21:53 2009